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CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer

BACKGROUND: CGRRF1 is a growth suppressor and consists of a transmembrane domain and a RING-finger domain. It functions as a RING domain E3 ubiquitin ligase involved in endoplasmic reticulum-associated degradation. The expression of CGRRF1 is decreased in cancer tissues; however, the role of CGRRF1...

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Detalles Bibliográficos
Autores principales:	Lee, Yu-Ju, Ho, Shiuh-Rong, Graves, Joshua D., Xiao, Yang, Huang, Shixia, Lin, Weei-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894136/ https://www.ncbi.nlm.nih.gov/pubmed/31801577 http://dx.doi.org/10.1186/s13058-019-1212-2

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