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Factors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening
BACKGROUND: The identification of cell-free fetal DNA (cffDNA) facilitated non-invasive prenatal screening (NIPS) through analysis of cffDNA in maternal plasma. However, challenges regarding its clinical implementation become apparent. Factors affecting fetal fraction should be clarified to guide it...
Autores principales: | Hou, Yaping, Yang, Jiexia, Qi, Yiming, Guo, Fangfang, Peng, Haishan, Wang, Dongmei, Wang, Yixia, Luo, Xiaohui, Li, Yi, Yin, Aihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894209/ https://www.ncbi.nlm.nih.gov/pubmed/31801621 http://dx.doi.org/10.1186/s40246-019-0244-0 |
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