Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial

BACKGROUND: Observational research suggests that combined therapy with Vitamin C, thiamine and hydrocortisone may reduce mortality in patients with septic shock. METHODS AND DESIGN: The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) trial is a multicenter, double-blind, adaptive sample size, ra...

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Detalles Bibliográficos
Autores principales: Lindsell, Christopher J., McGlothlin, Anna, Nwosu, Samuel, Rice, Todd W., Hall, Alex, Bernard, Gordon R., Busse, Laurence W., Ely, E. Wesley, Fowler, Alpha A., Gaieski, David F., Hinson, Jeremiah S., Hooper, Michael H., Jackson, James C., Kelen, Gabor D., Levine, Mark, Martin, Greg S., Rothman, Richard E., Sevransky, Jonathan E., Viele, Kert, Wright, David W., Hager, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894243/
https://www.ncbi.nlm.nih.gov/pubmed/31801567
http://dx.doi.org/10.1186/s13063-019-3775-8

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