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Tumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function

BACKGROUND: Regulatory T (T(reg)) cells have an immunosuppressive function in cancer, but the underlying mechanism of immunosuppression in the tumor microenvironment (TME) is unclear. METHODS: We compared the phenotypes of T cell subsets, including T(reg) cells, obtained from peripheral blood, malig...

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Detalles Bibliográficos
Autores principales:	Kim, Hye Ryun, Park, Hyo Jin, Son, Jimin, Lee, Jin Gu, Chung, Kyung Young, Cho, Nam Hoon, Shim, Hyo Sup, Park, Seyeon, Kim, Gamin, In Yoon, Hong, Kim, Hyun Gyung, Jung, Yong Woo, Cho, Byoung Chul, Park, Seong Yong, Rha, Sun Young, Ha, Sang-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894345/ https://www.ncbi.nlm.nih.gov/pubmed/31801611 http://dx.doi.org/10.1186/s40425-019-0785-8

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