Cargando…

Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival

BACKGROUND: The genomic landscape of head and neck cancer has been reported through The Cancer Genome Atlas project. We attempt to determine if high-risk human papillomavirus (HPV) or frequently mutated genes are correlated with survival in an oral cancer cohort. METHODS: Patient demographic data al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mundi, Neil, Prokopec, Stephenie D., Ghasemi, Farhad, Warner, Andrew, Patel, Krupal, MacNeil, Danielle, Howlett, Christopher, Stecho, William, Plantinga, Paul, Pinto, Nicole, Ruicci, Kara M., Khan, Mohammed Imran, Han, Myung Woul, Yoo, John, Fung, Kevin, Sahovaler, Axel, Palma, David A., Winquist, Eric, Mymryk, Joe S., Barrett, John W., Boutros, Paul C., Nichols, Anthony C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894507/ https://www.ncbi.nlm.nih.gov/pubmed/31844556 http://dx.doi.org/10.1186/s41199-019-0045-0

Ejemplares similares

Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models
por: Pinto, Nicole, et al.
Publicado: (2020)

TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
por: Ruicci, Kara M., et al.
Publicado: (2020)

Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Does HPV Subtype Predict Outcomes in Head and Neck Cancers?
por: Ziai, Hedyeh, et al.
Publicado: (2021)

Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
por: Gameiro, Steven F., et al.
Publicado: (2021)

Lestaurtinib is a potent inhibitor of anaplastic thyroid cancer cell line models
por: Pinto, Nicole, et al.
Publicado: (2018)

High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines
por: Ghasemi, Farhad, et al.
Publicado: (2018)

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer
por: Ghasemi, Farhad, et al.
Publicado: (2017)

Analysis of the TCGA Dataset Reveals that Subsites of Laryngeal Squamous Cell Carcinoma Are Molecularly Distinct
por: Sorgini, Alana, et al.
Publicado: (2020)

Detection of Circulating Tumor DNA in Patients with Thyroid Nodules
por: Patel, Krupal B., et al.
Publicado: (2021)

Introduction and expression of PIK3CA(E545K) in a papillary thyroid cancer BRAF(V600E) cell line leads to a dedifferentiated aggressive phenotype
por: Pinto, Nicole, et al.
Publicado: (2022)

Head and neck cancer patients declining curative treatment: a case series and literature review
por: Sahovaler, Axel, et al.
Publicado: (2021)

Treatment of early stage Supraglottic squamous cell carcinoma: meta-analysis comparing primary surgery versus primary radiotherapy
por: Patel, Krupal B., et al.
Publicado: (2018)

Utility of clinical features with fine needle aspiration biopsy for diagnosis of Warthin tumor
por: So, Thomas, et al.
Publicado: (2019)

Establishment of four head and neck squamous cell carcinoma cell lines: importance of reference DNA for accurate genomic characterisation
por: Patel, K B, et al.
Publicado: (2023)

Modern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution
por: Di Gravio, Eric J., et al.
Publicado: (2020)

Identification of Reference Proteins for Western Blot Analyses in Mouse Model Systems of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) Toxicity
por: Prokopec, Stephenie D., et al.
Publicado: (2014)

Functional outcomes in early (T1/T2) supraglottic cancer: a systematic review
por: van der Woerd, Benjamin, et al.
Publicado: (2018)

High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells
por: Gameiro, Steven F., et al.
Publicado: (2019)

A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases
por: Nichols, Anthony C., et al.
Publicado: (2013)

Genomically Driven Precision Medicine to Improve Outcomes in Anaplastic Thyroid Cancer
por: Pinto, Nicole, et al.
Publicado: (2014)

Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection
por: Gameiro, Steven F., et al.
Publicado: (2017)

3p Arm Loss and Survival in Head and Neck Cancer: An Analysis of TCGA Dataset
por: Kim, Hugh Andrew Jinwook, et al.
Publicado: (2021)

Transcriptomic Impact of IMA-08401, a Novel AHR Agonist Resembling Laquinimod, on Rat Liver
por: Prokopec, Stephenie D., et al.
Publicado: (2019)

Rapid standardized operating rooms (RAPSTOR) in thyroid and parathyroid surgery
por: Ernst, Hannah, et al.
Publicado: (2021)

Male and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
por: Lee, Jamie, et al.
Publicado: (2015)

Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
por: Gameiro, Steven F., et al.
Publicado: (2018)

2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity
por: Watson, John D., et al.
Publicado: (2016)

Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification
por: Zeng, Peter Y.F., et al.
Publicado: (2022)

Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome
por: Tessier, Tanner M., et al.
Publicado: (2020)

Sex differences in oncogenic mutational processes
por: Li, Constance H., et al.
Publicado: (2020)

A Population-Based Study of 30-day Incidence of Ischemic Stroke Following Surgical Neck Dissection
por: MacNeil, S. Danielle, et al.
Publicado: (2015)

VennDiagramWeb: a web application for the generation of highly customizable Venn and Euler diagrams
por: Lam, Felix, et al.
Publicado: (2016)

Survival-Associated Metabolic Genes in Human Papillomavirus-Positive Head and Neck Cancers
por: Prusinkiewicz, Martin A., et al.
Publicado: (2020)

2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver
por: Villaseñor-Altamirano, Ana B., et al.
Publicado: (2019)

Surgical margins of the oral cavity: is 5 mm really necessary?
por: Fowler, James, et al.
Publicado: (2022)

Clinical Presentation and Genomic Analysis of HPV-Related Squamous Cell Carcinoma of the Larynx in Two Young Female Patients
por: Taboun, Zahra, et al.
Publicado: (2023)

Does HPV type affect outcome in oropharyngeal cancer?
por: Nichols, Anthony C, et al.
Publicado: (2013)

Viral Retasking of hBre1/RNF20 to Recruit hPaf1 for Transcriptional Activation
por: Fonseca, Gregory J., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b0is98vpi3gbfb6t6br0vakjuq