Cargando…
In Vivo Bone Effects of a Novel Bisphosphonate‐EP4a Conjugate Drug (C3) for Reversing Osteoporotic Bone Loss in an Ovariectomized Rat Model
Pathological bone loss is a regular feature of postmenopausal osteoporosis, and the microstructural changes along with the bone loss make the individual prone to getting hip, spine, and wrist fractures. We have developed a new conjugate drug named C3, which has a synthetic, stable EP4 agonist (EP4a)...
Autores principales: | Sheikh, Zeeshan, Chen, Gang, Al‐Jaf, Faik, Thévenin, Marion, Banks, Kate, Glogauer, Michael, Young, Robert N, Grynpas, Marc D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894726/ https://www.ncbi.nlm.nih.gov/pubmed/31844825 http://dx.doi.org/10.1002/jbm4.10237 |
Ejemplares similares
-
Natural graft tissues and synthetic biomaterials for periodontal and alveolar bone reconstructive applications: a review
por: Sheikh, Zeeshan, et al.
Publicado: (2017) -
Scopolin Attenuates Osteoporotic Bone Loss in Ovariectomized Mice
por: Park, Eunkuk, et al.
Publicado: (2020) -
Bone Replacement Materials and Techniques Used for Achieving Vertical Alveolar Bone Augmentation
por: Sheikh, Zeeshan, et al.
Publicado: (2015) -
The Beneficial Effects of Bisphosphonate-enoxacin on Cortical Bone Mass and Strength in Ovariectomized Rats
por: Liu, Xuqiang, et al.
Publicado: (2017) -
Bisphosphonate conjugation for bone specific drug targeting
por: Farrell, Kristen B., et al.
Publicado: (2018)