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Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Lepr(db)/J mouse model of non-alcoholic fatty liver disease (NAFLD)
Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern. With a propensity to progress towards non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma, NAFLD is an important link amongst a multitude of comorbidities including obesity, diabetes, and cardiova...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894821/ https://www.ncbi.nlm.nih.gov/pubmed/31805072 http://dx.doi.org/10.1371/journal.pone.0225604 |