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Bilateral Parkinson’s disease model rats exhibit hyperalgesia to subcutaneous formalin administration into the vibrissa pad
We bilaterally injected 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle of rats and developed bilateral Parkinson’s disease (PD) model rats in order to experimentally investigate the neural mechanisms underlying the alteration of nociception in the orofacial region of patients with PD. W...
Autores principales: | Maegawa, Hiroharu, Adachi, Nayuka, Hanamoto, Hiroshi, Kudo, Chiho, Niwa, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894844/ https://www.ncbi.nlm.nih.gov/pubmed/31805115 http://dx.doi.org/10.1371/journal.pone.0225928 |
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