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Local, nonlinear effects of cGMP and Ca(2+) reduce single photon response variability in retinal rods
The single photon response (SPR) in vertebrate photoreceptors is inherently variable due to several stochastic events in the phototransduction cascade, the main one being the shutoff of photoactivated rhodopsin. Deactivation is driven by a random number of steps, each of random duration with final q...
Autores principales: | Caruso, Giovanni, Gurevich, Vsevolod V., Klaus, Colin, Hamm, Heidi, Makino, Clint L., DiBenedetto, Emmanuele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894879/ https://www.ncbi.nlm.nih.gov/pubmed/31805112 http://dx.doi.org/10.1371/journal.pone.0225948 |
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