Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

Extrinsic cues trigger the local translation of specific mRNAs in growing axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals to local translation but it is not known how broadly this mechanism operates, nor whether it can selecti...

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Detalles Bibliográficos
Autores principales: Koppers, Max, Cagnetta, Roberta, Shigeoka, Toshiaki, Wunderlich, Lucia CS, Vallejo-Ramirez, Pedro, Qiaojin Lin, Julie, Zhao, Sixian, Jakobs, Maximilian AH, Dwivedy, Asha, Minett, Michael S, Bellon, Anaïs, Kaminski, Clemens F, Harris, William A, Flanagan, John G, Holt, Christine E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894925/
https://www.ncbi.nlm.nih.gov/pubmed/31746735
http://dx.doi.org/10.7554/eLife.48718

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