4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth

The improvement of body’s own immune system is considered one of the safest approaches to fight against cancer and several other diseases. Excessive catabolism of the essential amino acid, L-tryptophan (L-Trp) assists the cancer cells to escape normal immune obliteration. The formation of disproport...

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Detalles Bibliográficos
Autores principales: Panda, Subhankar, Pradhan, Nirmalya, Chatterjee, Soumya, Morla, Sudhir, Saha, Abhishek, Roy, Ashalata, Kumar, Sachin, Bhattacharyya, Arindam, Manna, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895048/
https://www.ncbi.nlm.nih.gov/pubmed/31804586
http://dx.doi.org/10.1038/s41598-019-54963-9

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