Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer

Clear cell renal cell carcinoma (ccRCC) is known for its highly vascular phenotype which is associated with elevated expression of vascular endothelial growth factor A (VEGF), also known as vascular permeability factor (VPF). Accordingly, VEGF has been an attractive target for antiangiogenic therapi...

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Detalles Bibliográficos
Autores principales: Pal, Krishnendu, Madamsetty, Vijay Sagar, Dutta, Shamit Kumar, Wang, Enfeng, Angom, Ramcharan Singh, Mukhopadhyay, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895165/
https://www.ncbi.nlm.nih.gov/pubmed/31840081
http://dx.doi.org/10.1038/s41698-019-0105-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895165/
https://www.ncbi.nlm.nih.gov/pubmed/31840081
http://dx.doi.org/10.1038/s41698-019-0105-2

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