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Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer
Clear cell renal cell carcinoma (ccRCC) is known for its highly vascular phenotype which is associated with elevated expression of vascular endothelial growth factor A (VEGF), also known as vascular permeability factor (VPF). Accordingly, VEGF has been an attractive target for antiangiogenic therapi...
Autores principales: | Pal, Krishnendu, Madamsetty, Vijay Sagar, Dutta, Shamit Kumar, Wang, Enfeng, Angom, Ramcharan Singh, Mukhopadhyay, Debabrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895165/ https://www.ncbi.nlm.nih.gov/pubmed/31840081 http://dx.doi.org/10.1038/s41698-019-0105-2 |
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