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Unpacking the aggregation-oligomerization-fibrillization process of naturally-occurring hIAPP amyloid oligomers isolated directly from sera of children with obesity or diabetes mellitus

The formation of amyloid oligomers and fibrils of the human islet amyloid polypeptide (hIAPP) has been linked with β- cell failure and death which causes the onset, progression, and comorbidities of diabetes. We begin to unpack the aggregation-oligomerization-fibrillization process of these oligomer...

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Detalles Bibliográficos
Autores principales:	Altamirano-Bustamante, Myriam M., Altamirano-Bustamante, Nelly F., Larralde-Laborde, Mateo, Lara-Martínez, Reyna, Leyva-García, Edgar, Garrido-Magaña, Eulalia, Rojas, Gerardo, Jiménez-García, Luis Felipe, Revilla-Monsalve, Cristina, Altamirano, Perla, Calzada-León, Raúl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895187/ https://www.ncbi.nlm.nih.gov/pubmed/31804529 http://dx.doi.org/10.1038/s41598-019-54570-8

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