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A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase
Human norovirus is the leading cause of acute gastroenteritis worldwide, affecting every year 685 million people. In about one third of cases, this virus affects children under five years of age, causing each year up to 200,000 child deaths, mainly in the developing countries. Norovirus outbreaks ar...
Autores principales: | Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T., Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895199/ https://www.ncbi.nlm.nih.gov/pubmed/31804593 http://dx.doi.org/10.1038/s41598-019-54903-7 |
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