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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited acti...

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Detalles Bibliográficos
Autores principales:	Wang, Zhiyong, Wu, Victoria H., Allevato, Michael M., Gilardi, Mara, He, Yudou, Luis Callejas-Valera, Juan, Vitale-Cross, Lynn, Martin, Daniel, Amornphimoltham, Panomwat, Mcdermott, James, Yung, Bryan S., Goto, Yusuke, Molinolo, Alfredo A., Sharabi, Andrew B., Cohen, Ezra E. W., Chen, Qianming, Lyons, J. Guy, Alexandrov, Ludmil B., Gutkind, J. Silvio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895221/ https://www.ncbi.nlm.nih.gov/pubmed/31804466 http://dx.doi.org/10.1038/s41467-019-13471-0

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