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CRISPR DNA elements controlling site-specific spacer integration and proper repeat length by a Type II CRISPR–Cas system

CRISPR–Cas systems provide heritable immunity against viruses by capturing short invader DNA sequences, termed spacers, and incorporating them into the CRISPR loci of the prokaryotic host genome. Here, we investigate DNA elements that control accurate spacer uptake in the type II-A CRISPR locus of S...

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Detalles Bibliográficos
Autores principales:	Kim, Jenny G, Garrett, Sandra, Wei, Yunzhou, Graveley, Brenton R, Terns, Michael P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895254/ https://www.ncbi.nlm.nih.gov/pubmed/31392984 http://dx.doi.org/10.1093/nar/gkz677

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