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Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B

DNA repair is critical for maintaining genomic integrity. Finding DNA lesions initiates the entire repair process. In human nucleotide excision repair (NER), XPC-RAD23B recognizes DNA lesions and recruits downstream factors. Although previous studies revealed the molecular features of damage identif...

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Detalles Bibliográficos
Autores principales:	Cheon, Na Young, Kim, Hyun-Suk, Yeo, Jung-Eun, Schärer, Orlando D, Lee, Ja Yil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895271/ https://www.ncbi.nlm.nih.gov/pubmed/31372632 http://dx.doi.org/10.1093/nar/gkz629

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