PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function

Heme is an essential prosthetic group of numerous proteins and a central signaling molecule in many physiologic processes(1,2). The chemical reactivity of heme requires that a network of intracellular chaperone proteins exist to avert the cytotoxic effects of free heme, but the constituents of such...

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Detalles Bibliográficos
Autores principales: Galmozzi, Andrea, Kok, Bernard P., Kim, Arthur S., Montenegro-Burke, J. Rafael, Lee, Jae Y., Spreafico, Roberto, Mosure, Sarah, Albert, Verena, Cintron-Colon, Rigo, Godio, Cristina, Webb, William R., Conti, Bruno, Solt, Laura A., Kojetin, Douglas, Parker, Christopher G., Peluso, John J., Pru, James K., Siuzdak, Gary, Cravatt, Benjamin F., Saez, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895438/
https://www.ncbi.nlm.nih.gov/pubmed/31748741
http://dx.doi.org/10.1038/s41586-019-1774-2

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