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Targeting senescent cells in translational medicine

Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress and is considered a hallmark of ageing. Senescent cells accumulate in mu...

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Detalles Bibliográficos
Autores principales: Paez‐Ribes, Marta, González‐Gualda, Estela, Doherty, Gary J, Muñoz‐Espín, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895604/
https://www.ncbi.nlm.nih.gov/pubmed/31746100
http://dx.doi.org/10.15252/emmm.201810234