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Antineoplastic Effect of a Combined Mitotane Treatment/Ionizing Radiation in Adrenocortical Carcinoma: A Preclinical Study

Mitotane (MTT) is an adrenolytic drug used in adjuvant and advanced treatments of adrenocortical carcinoma (ACC). Ionizing radiation (IR) is also used in adrenal cancer treatment, even though its biological action remains unknown. To provide a reliable in vivo preclinical model of ACC, we used mouse...

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Detalles Bibliográficos
Autores principales: Cerquetti, Lidia, Bucci, Barbara, Carpinelli, Giulia, Lardo, Pina, Proietti, Antonella, Saporito, Raffaele, Rindi, Guido, Petrangeli, Elisa, Toscano, Vincenzo, Stigliano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895792/
https://www.ncbi.nlm.nih.gov/pubmed/31717612
http://dx.doi.org/10.3390/cancers11111768