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Improved Anti-Tumour Adaptive Immunity Can Overcome the Melanoma Immunosuppressive Tumour Microenvironment

Clinical benefits obtained from checkpoint blockade regimens demonstrate the importance of overcoming the immunosuppressive tumour microenvironment (TME) in cancer immunotherapy. Intravenous (i.v.) injection of B16 melanoma cells (H-2K(b)) leads to lethal disseminated pulmonary metastasis in Balb/c...

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Detalles Bibliográficos
Autores principales: Dang, Nana, Waer, Mark, Sprangers, Ben, Lin, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895810/
https://www.ncbi.nlm.nih.gov/pubmed/31683642
http://dx.doi.org/10.3390/cancers11111694