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Nucleocytoplasmic Shuttling of STATs. A Target for Intervention?
Signal transducer and activator of transcription (STAT) proteins are transcription factors that in the latent state are located predominantly in the cytoplasm. Activation of STATs through phosphorylation of a single tyrosine residue results in nuclear translocation. The requirement of tyrosine phosp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895884/ https://www.ncbi.nlm.nih.gov/pubmed/31752278 http://dx.doi.org/10.3390/cancers11111815 |