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Tumor Mutational Burden and Efficacy of Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis
Tumor mutational burden (TMB) is a genomic biomarker that predicts favorable responses to immune checkpoint inhibitors (ICIs). Here, we set out to assess the predictive value of TMB on long-term survival outcomes in patients undergoing ICIs. We systematically searched PubMed, Embase, CENTRAL and cli...
Autores principales: | Kim, Jong Yeob, Kronbichler, Andreas, Eisenhut, Michael, Hong, Sung Hwi, van der Vliet, Hans J., Kang, Jeonghyun, Shin, Jae Il, Gamerith, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895916/ https://www.ncbi.nlm.nih.gov/pubmed/31731749 http://dx.doi.org/10.3390/cancers11111798 |
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