Cargando…

Mechanisms of Graft-versus-Host Disease Prevention by Post-transplantation Cyclophosphamide: An Evolving Understanding

Post-transplantation cyclophosphamide (PTCy) has been highly successful at preventing severe acute and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT). The clinical application of this approach was based on extensive studies in major histocompatibil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nunes, Natalia S., Kanakry, Christopher G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895959/ https://www.ncbi.nlm.nih.gov/pubmed/31849930 http://dx.doi.org/10.3389/fimmu.2019.02668

Ejemplares similares

Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4(+) T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation
por: Hadjis, Ashley D., et al.
Publicado: (2022)

Extracellular Vesicles as Biomarkers of Acute Graft-vs.-Host Disease After Haploidentical Stem Cell Transplantation and Post-Transplant Cyclophosphamide
por: Lia, Giuseppe, et al.
Publicado: (2022)

Elafin as a Predictive Biomarker of Acute Skin Graft-Versus-Host Disease After Haploidentical Stem Cell Transplantation Using Post-Transplant High-Dose Cyclophosphamide
por: Solán, Laura, et al.
Publicado: (2021)

Post-transplant cyclophosphamide prevents xenogeneic graft-versus-host disease while depleting proliferating regulatory T cells
por: Ritacco, Caroline, et al.
Publicado: (2023)

Post-transplant cyclophosphamide versus anti-thymocyte globulin for graft-versus-host disease prevention in haploidentical transplantation for adult acute lymphoblastic leukemia
por: Nagler, Arnon, et al.
Publicado: (2020)

Comparison of alemtuzumab, anti-thymocyte globulin, and post-transplant cyclophosphamide for graft-versus-host disease and graft-versus-leukemia in murine models
por: Mashima, Kiyomi, et al.
Publicado: (2021)

Partially replacing cyclophosphamide with bendamustine in combination with cyclosporine A improves survival and reduces xenogeneic graft-versus-host-disease
por: Gilman, Kristy E., et al.
Publicado: (2023)

Minnesota acute graft-versus-host disease risk score predicts survival at onset of graft-versus-host disease after post-transplant cyclophosphamide prophylaxis
por: Ardizzoia, Federica, et al.
Publicado: (2022)

Low-dose anti-thymocyte globulin plus low-dose post-transplant cyclophosphamide-based regimen for prevention of graft-versus-host disease after haploidentical peripheral blood stem cell transplants: a large sample, long-term follow-up retrospective study
por: Li, Xingying, et al.
Publicado: (2023)

A Review of Cyclophosphamide-Induced Transplantation Tolerance in Mice and Its Relationship With the HLA-Haploidentical Bone Marrow Transplantation/Post-Transplantation Cyclophosphamide Platform
por: Mayumi, Hisanori
Publicado: (2021)

Unraveling the Mechanisms of Cutaneous Graft-Versus-Host Disease
por: Santos e Sousa, Pedro, et al.
Publicado: (2018)

“Phage Transplantation in Allotransplantation”: Possible Treatment in Graft-Versus-Host Disease?
por: Górski, Andrzej, et al.
Publicado: (2018)

Danger Signals and Graft-versus-host Disease: Current Understanding and Future Perspectives
por: Toubai, Tomomi, et al.
Publicado: (2016)

Graft Cryopreservation Does Not Impact Overall Survival after Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for Graft-versus-Host Disease Prophylaxis
por: Hamadani, Mehdi, et al.
Publicado: (2020)

Post-Transplant Cyclophosphamide for the Prevention of Graft-vs.-Host Disease in Allogeneic Hematopoietic Cell Transplantation: A Guide to Management for the Advanced Practitioner
por: Kachur, Ekaterina, et al.
Publicado: (2023)

The Role of Pattern-Recognition Receptors in Graft-Versus-Host Disease and Graft-Versus-Leukemia after Allogeneic Stem Cell Transplantation
por: Heidegger, Simon, et al.
Publicado: (2014)

Post Transplantation Bilirubin Nanoparticles Ameliorate Murine Graft Versus Host Disease via a Reduction of Systemic and Local Inflammation
por: Pareek, Sumedha, et al.
Publicado: (2022)

Use of Post-transplant Cyclophosphamide Treatment to Build a Tolerance Platform to Prevent Liquid and Solid Organ Allograft Rejection
por: Lightbourn, Casey O., et al.
Publicado: (2021)

Bone Marrow versus Peripheral Blood Grafts for Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide
por: Mehta, Rohtesh S., et al.
Publicado: (2021)

Post-Transplant Cyclophosphamide and Thymoglobulin, a Graft-Versus-Host Disease Prophylaxis in Matched Sibling Donor Peripheral Blood Stem Cell Transplantations
por: Kunacheewa, Chutima, et al.
Publicado: (2020)

Post-transplant cyclophosphamide and sirolimus based graft-versus-host disease prophylaxis after allogeneic stem cell transplantation for acute myeloid leukemia
por: Lazzari, Lorenzo, et al.
Publicado: (2022)

Editorial: The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation
por: Mancusi, Antonella, et al.
Publicado: (2020)

T Cell Subsets in Graft Versus Host Disease and Graft Versus Tumor
por: Jiang, Hua, et al.
Publicado: (2021)

THE INDUCTION OF GRAFT VERSUS HOST DISEASE IN MICE TREATED WITH CYCLOPHOSPHAMIDE
por: Owens, Albert H., et al.
Publicado: (1968)

Letermovir Administration to Prevent Cytomegalovirus Reactivation Is the Potential Risk of Chronic Graft-Versus-Host Disease in Patients Who Received Haploidentical Stem-Cell Transplantation With Post-Transplant Cyclophosphamide
por: Terao, Toshiki, et al.
Publicado: (2021)

Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia Effect
por: Huang, Ying, et al.
Publicado: (2022)

Interleukin-6 as Biomarker for Acute GvHD and Survival After Allogeneic Transplant With Post-transplant Cyclophosphamide
por: Greco, Raffaella, et al.
Publicado: (2019)

Interleukin-22 in Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation
por: Lamarthée, Baptiste, et al.
Publicado: (2016)

Translational Clinical Strategies for the Prevention of Gastrointestinal Tract Graft Versus Host Disease
por: Rayasam, Aditya, et al.
Publicado: (2021)

P1371: GRAFT-VERSUS-HOST DISEASE OFFERS NO GRAFT-VERSUS-LEUKEMIA ADVANTAGE IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA AFTER HAPLO-IDENTICAL STEM CELL TRANSPLANTATION WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE
por: Shimoni, A., et al.
Publicado: (2022)

NOTCH and Graft-Versus-Host Disease
por: Di Ianni, Mauro, et al.
Publicado: (2018)

Editorial on Translational Research in Graft-Versus-Host Disease (GVHD) and Graft-Versus-Tumor (GVT) Effect After Allogeneic Hematopoietic Cell Transplantation
por: Czech, Marie, et al.
Publicado: (2022)

Post-transplantation Cyclophosphamide: From HLA-Haploidentical to Matched-Related and Matched-Unrelated Donor Blood and Marrow Transplantation
por: Williams, Louis, et al.
Publicado: (2020)

Immune Reconstitution and Graft-Versus-Host Reactions in Rat Models of Allogeneic Hematopoietic Cell Transplantation
por: Zinöcker, Severin, et al.
Publicado: (2012)

Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation
por: Simonetta, Federico, et al.
Publicado: (2017)

Mesenchymal Stromal Cells for Graft Versus Host Disease: Mechanism-Based Biomarkers
por: Cheung, Tik Shing, et al.
Publicado: (2020)

Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice
por: Khuat, Lam T., et al.
Publicado: (2021)

Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease
por: Le, Hongnga T., et al.
Publicado: (2020)

Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease
por: Mohamed, Fathima A., et al.
Publicado: (2021)

Editorial: Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD)
por: Ullrich, Evelyn, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8ccluptl87cr9nr7gtrnd2b73o