Cargando…

Targeted-Gene Sequencing to Catch Triple Negative Breast Cancer Heterogeneity before and after Neoadjuvant Chemotherapy

Triple negative breast cancer (TNBC) patients not attaining pathological Complete Response (pCR) after neo-adjuvant chemotherapy (NAC) have poor prognosis. We characterized 19 patients for somatic mutations in primary tumor biopsy and residual disease (RD) at surgery by 409 cancer-related gene seque...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Cosimo, Serena, Appierto, Valentina, Silvestri, Marco, Pruneri, Giancarlo, Vingiani, Andrea, Perrone, Federica, Busico, Adele, Folli, Secondo, Scaperrotta, Gianfranco, de Braud, Filippo Guglielmo, Bianchi, Giulia Valeria, Cavalieri, Stefano, Daidone, Maria Grazia, Dugo, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895966/
https://www.ncbi.nlm.nih.gov/pubmed/31717320
http://dx.doi.org/10.3390/cancers11111753