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Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation

Deregulation of different intracellular signaling pathways is a common feature in cancer. Numerous studies indicate that persistent activation of the phosphoinositide 3-kinase (PI3K) pathway is often observed in cancer cells. 3-phosphoinositide dependent protein kinase-1 (PDK1), a transducer protein...

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Detalles Bibliográficos
Autores principales:	Casari, Ilaria, Domenichini, Alice, Sestito, Simona, Capone, Emily, Sala, Gianluca, Rapposelli, Simona, Falasca, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896057/ https://www.ncbi.nlm.nih.gov/pubmed/31683659 http://dx.doi.org/10.3390/cancers11111695

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