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The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells
One of the most significant therapeutic challenges in the treatment of ovarian cancer is the development of recurrent platinum-resistant disease. Cancer stem cells (CSCs) are postulated to contribute to recurrent and platinum-resistant ovarian cancer (OvCa). Drugs that selectively target CSCs may au...
Autores principales: | Bellio, Chiara, DiGloria, Celeste, Spriggs, David R., Foster, Rosemary, Growdon, Whitfield B., Rueda, Bo R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896080/ https://www.ncbi.nlm.nih.gov/pubmed/31671803 http://dx.doi.org/10.3390/cancers11111678 |
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