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PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target
Molecular assessment of colorectal cancer (CRC) is receiving growing attention, beyond RAS and BRAF, because of its influence on prognosis and prediction in cancer treatment. PTEN (phosphatase and tensin homologue), a tumor suppressor, regulating cell division and apoptosis, has been explored, and s...
Autores principales: | Salvatore, Lisa, Calegari, Maria Alessandra, Loupakis, Fotios, Fassan, Matteo, Di Stefano, Brunella, Bensi, Maria, Bria, Emilio, Tortora, Giampaolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896095/ https://www.ncbi.nlm.nih.gov/pubmed/31717544 http://dx.doi.org/10.3390/cancers11111765 |
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