A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast Cancer

Radiation therapy (RT) is one of the main treatments for triple-negative breast cancer (TNBC). However, many patients experience RT failure due to the metastatic potential of RT and the radiation resistance of several cancers. Histone deacetylase inhibitors (HDACis) can serve as radiosensitizers. In...

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Detalles Bibliográficos
Autores principales: Chiu, Hui-Wen, Yeh, Ya-Ling, Ho, Sheng-Yow, Wu, Yuan-Hua, Wang, Bour-Jr, Huang, Wei-Jan, Ho, Yuan-Soon, Wang, Ying-Jan, Chen, Li-Ching, Tu, Shih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896096/
https://www.ncbi.nlm.nih.gov/pubmed/31683883
http://dx.doi.org/10.3390/cancers11111703

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