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Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer
Double strand breaks (DSBs) are induced in the DNA following exposure of cells to ionizing radiation (IR) and are highly consequential for genome integrity, requiring highly specialized modes of processing. Erroneous processing of DSBs is a cause of cell death or its transformation to a cancer cell....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896103/ https://www.ncbi.nlm.nih.gov/pubmed/31661831 http://dx.doi.org/10.3390/cancers11111671 |