A Bi-Exponential Repair Algorithm for Radiation-Induced Double-Strand Breaks: Application to Simulation of Chromosome Aberrations

Background: Radiation induces DNA double-strand breaks (DSBs), and chromosome aberrations (CA) form during the DSBs repair process. Several methods have been used to model the repair kinetics of DSBs including the bi-exponential model, i.e., N(t) = N(1)exp(−t/τ(1)) + N(2)exp(−t/τ(2)), where N(t) is...

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Detalles Bibliográficos
Autores principales: Plante, Ianik, Slaba, Tony, Shavers, Zarana, Hada, Megumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896174/
https://www.ncbi.nlm.nih.gov/pubmed/31744120
http://dx.doi.org/10.3390/genes10110936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896174/
https://www.ncbi.nlm.nih.gov/pubmed/31744120
http://dx.doi.org/10.3390/genes10110936

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