Cargando…

NOP53 as A Candidate Modifier Locus for Familial Non-Medullary Thyroid Cancer

Nonsyndromic familial non-medullary thyroid cancer (FNMTC) represents 3–9% of thyroid cancers, but the susceptibility gene(s) remain unknown. We designed this multicenter study to analyze families with nonsyndromic FNMTC and identify candidate susceptibility genes. We performed exome sequencing of D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Orois, Aida, Gara, Sudheer K., Mora, Mireia, Halperin, Irene, Martínez, Sandra, Alfayate, Rocio, Kebebew, Electron, Oriola, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896177/ https://www.ncbi.nlm.nih.gov/pubmed/31703244 http://dx.doi.org/10.3390/genes10110899

Ejemplares similares

To the editor
por: Kebebew, Electron, et al.
Publicado: (2017)

Co-Occurrence of Familial Non-Medullary Thyroid Cancer (FNMTC) and Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Associated Tumors—A Cohort Study
por: Aswath, Kshama, et al.
Publicado: (2021)

Medullary Thyroid Cancer: It is a pain in the neck?
por: Guerrero, Marlon A., et al.
Publicado: (2011)

MiR-886-3p Regulates Cell Proliferation and Migration, and Is Dysregulated in Familial Non-Medullary Thyroid Cancer
por: Xiong, Yin, et al.
Publicado: (2011)

Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors
por: Gara, Sudheer Kumar, et al.
Publicado: (2018)

GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3
por: Gara, Sudheer Kumar, et al.
Publicado: (2020)

MiR-20a Is Upregulated in Anaplastic Thyroid Cancer and Targets LIMK1
por: Xiong, Yin, et al.
Publicado: (2014)

Carfilzomib potentiates CUDC-101-induced apoptosis in anaplastic thyroid cancer
por: Zhang, Lisa, et al.
Publicado: (2016)

Editorial: Translational Research in Thyroid Cancer
por: Vasko, Vasyl, et al.
Publicado: (2020)

Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples
por: Gara, Sudheer Kumar, et al.
Publicado: (2015)

Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response
por: Nilubol, Naris, et al.
Publicado: (2018)

miR-126-3p Inhibits Thyroid Cancer Cell Growth and Metastasis, and Is Associated with Aggressive Thyroid Cancer
por: Xiong, Yin, et al.
Publicado: (2015)

Biomarkers in Thyroid Tumor Research: New Diagnostic Tools and Potential Targets of Molecular-Based Therapy
por: Gimm, Oliver, et al.
Publicado: (2011)

SAT-568 Glutamine Metabolism Is a New Potential Therapeutic Target in Aggressive Thyroid Cancer
por: Patel, Dhaval, et al.
Publicado: (2019)

RARRES2 functions as a tumor suppressor by promoting β-catenin phosphorylation/degradation and inhibiting p38 phosphorylation in adrenocortical carcinoma
por: Liu-Chittenden, Yi, et al.
Publicado: (2017)

NOP53 Suppresses Autophagy through ZKSCAN3-Dependent and -Independent Pathways
por: Cho, Young-Eun, et al.
Publicado: (2021)

Further evidence for a parent-of-origin effect at the NOP9 locus on language-related phenotypes
por: Pettigrew, Kerry A., et al.
Publicado: (2016)

Management Options for Advanced Low or Intermediate Grade Gastroenteropancreatic Neuroendocrine Tumors: Review of Recent Literature
por: Neychev, Vladimir, et al.
Publicado: (2017)

CD276 as a Candidate Target for Immunotherapy in Medullary Thyroid Cancer
por: Hińcza-Nowak, Kinga, et al.
Publicado: (2023)

Novel Point Mutations and Allele Loss at the RET Locus in Sporadic Medullary Thyroid Carcinomas
por: Uchino, Shinya, et al.
Publicado: (1998)

NOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance
por: Shi, Jie, et al.
Publicado: (2022)

Adrenocortical Carcinoma and Synchronous Malignancies
por: Guerrero, Marlon A., et al.
Publicado: (2010)

Inactivation of the p53 Gene Is not Required for Tumorigenesis of Medullary Thyroid Carcinoma or Pheochromocytoma
por: Yana, Ikuo, et al.
Publicado: (1992)

Sprouty1 is a candidate tumor suppressor gene in medullary thyroid carcinoma
por: Macià, Anna, et al.
Publicado: (2011)

Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53
por: Falk, Sebastian, et al.
Publicado: (2017)

Cytoplasmic Translocation of Nucleolar Protein NOP53 Promotes Viral Replication by Suppressing Host Defense
por: Meng, Wen, et al.
Publicado: (2018)

Thyroid: Medullary Carcinoma
por: Somnay, Yash R., et al.
Publicado: (2013)

Parkinson’s disease: no NOP, new hope
por: Arcuri, Ludovico, et al.
Publicado: (2016)

A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58
por: Westman, Belinda J., et al.
Publicado: (2010)

Analysis of loss of heterozygsity effect on thyroid tumor with oxyphilia cell locus in familial non medullary thyroid carcinoma in Iranian families
por: Shirazi, Hasti Atashi, et al.
Publicado: (2012)

Prognostic Influence of Clinical and Pathological Factors in Medullary Thyroid Carcinoma: A Study of 53 Cases
por: Brandão, Lenine G., et al.
Publicado: (2009)

Medullary carcinoma of the thyroid gland.
por: Russell, C.
Publicado: (1980)

Diagnosis of medullary thyroid cancer
por: Marchisotta, Stefania, et al.
Publicado: (2009)

Medullary carcinoma of the thyroid: an update
por: Alevizaki, Maria
Publicado: (2013)

Pediatric Medullary Thyroid Carcinoma
por: Starenki, Dmytro, et al.
Publicado: (2015)

The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
por: Cámara-Quílez, María, et al.
Publicado: (2020)

The roles of NOP56 in cancer and SCA36
por: Zhao, Shimin, et al.
Publicado: (2023)

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer
por: Jee, Youn Hee, et al.
Publicado: (2016)

Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis
por: Sadowski, Samira M., et al.
Publicado: (2015)

International Medullary Thyroid Carcinoma Grading System: A Validated Grading System for Medullary Thyroid Carcinoma
por: Xu, Bin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_knnlqule4dsjmvb5o321pcpcgq