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PipeMEM: A Framework to Speed Up BWA-MEM in Spark with Low Overhead

(1) Background: DNA sequence alignment process is an essential step in genome analysis. BWA-MEM has been a prevalent single-node tool in genome alignment because of its high speed and accuracy. The exponentially generated genome data requiring a multi-node solution to handle large volumes of data cu...

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Detalles Bibliográficos
Autores principales: Zhang, Lingqi, Liu, Cheng, Dong, Shoubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896194/
https://www.ncbi.nlm.nih.gov/pubmed/31689965
http://dx.doi.org/10.3390/genes10110886