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Mononuclear but Not Polymorphonuclear Phagocyte Depletion Increases Circulation Times and Improves Mammary Tumor-Homing Efficiency of Donor Bone Marrow-Derived Monocytes
Tumor associated macrophages are an essential part of the tumor microenvironment. Consequently, bone marrow-derived monocytes (BMDMs) are continuously recruited to tumors and are therefore seen as ideal delivery vehicles with tumor-targeting properties. By using immune cell depleting agents and macr...
Autores principales: | Combes, Francis, Sofias, Alexandros Marios, Mc Cafferty, Séan, Huysmans, Hanne, De Temmerman, Joyca, Hak, Sjoerd, Meyer, Evelyne, Sanders, Niek N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896201/ https://www.ncbi.nlm.nih.gov/pubmed/31717301 http://dx.doi.org/10.3390/cancers11111752 |
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