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Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences
Variation in the enzymatic activity of pharmacogenes is defined by star alleles (haplotypes) comprised of single‐nucleotide variants, small insertion‐deletions, and large structural variants. We recently developed Stargazer, a next‐generation sequencing‐based tool to call star alleles for the clinic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896231/ https://www.ncbi.nlm.nih.gov/pubmed/31206625 http://dx.doi.org/10.1002/cpt.1552 |