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A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit

During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) differentiate. Usi...

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Detalles Bibliográficos
Autores principales: Sladitschek, Hanna L, Neveu, Pierre A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896232/
https://www.ncbi.nlm.nih.gov/pubmed/31885203
http://dx.doi.org/10.15252/msb.20199043