Cargando…
A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit
During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) differentiate. Usi...
Autores principales: | Sladitschek, Hanna L, Neveu, Pierre A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896232/ https://www.ncbi.nlm.nih.gov/pubmed/31885203 http://dx.doi.org/10.15252/msb.20199043 |
Ejemplares similares
-
The bimodally expressed microRNA miR‐142 gates exit from pluripotency
por: Sladitschek, Hanna L, et al.
Publicado: (2015) -
A transcribed enhancer dictates mesendoderm specification in pluripotency
por: Alexanian, Michael, et al.
Publicado: (2017) -
Uncovering the mesendoderm gene regulatory network through multi-omic data integration
por: Jansen, Camden, et al.
Publicado: (2022) -
Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo
por: Bessodes, Nathalie, et al.
Publicado: (2012) -
Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression
por: Nelson, Andrew C, et al.
Publicado: (2014)