The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon

BACKGROUND: Nonstructural protein 1 (NS1) is a virulence factor encoded by influenza A virus (IAV) that is expressed in the nucleus and cytoplasm of host cells during the earliest stages of infection. NS1 is a multifunctional protein that plays an important role in virus replication, virulence and i...

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Detalles Bibliográficos
Autores principales: Cheng, Jinghua, Tao, Jie, Li, Benqiang, Shi, Ying, Liu, Huili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896355/
https://www.ncbi.nlm.nih.gov/pubmed/31805964
http://dx.doi.org/10.1186/s12985-019-1255-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896355/
https://www.ncbi.nlm.nih.gov/pubmed/31805964
http://dx.doi.org/10.1186/s12985-019-1255-0

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