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Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study

INTRODUCTION: Pruritic papular eruption (PPE) remains as one of the most common cutaneous manifestations in HIV-infected patients. Proper knowledge about understanding the risk factors associated with this disease may help to decrease the prevalence of PPE. OBJECTIVE: The present study was conducted...

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Autores principales: Mohammed, Shoubin, Vellaisamy, Seethalakshmi Ganga, Gopalan, Kannan, Sukumaran, Lekha, Valan, A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896392/
https://www.ncbi.nlm.nih.gov/pubmed/31922105
http://dx.doi.org/10.4103/ijstd.IJSTD_69_18
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author Mohammed, Shoubin
Vellaisamy, Seethalakshmi Ganga
Gopalan, Kannan
Sukumaran, Lekha
Valan, A. S.
author_facet Mohammed, Shoubin
Vellaisamy, Seethalakshmi Ganga
Gopalan, Kannan
Sukumaran, Lekha
Valan, A. S.
author_sort Mohammed, Shoubin
collection PubMed
description INTRODUCTION: Pruritic papular eruption (PPE) remains as one of the most common cutaneous manifestations in HIV-infected patients. Proper knowledge about understanding the risk factors associated with this disease may help to decrease the prevalence of PPE. OBJECTIVE: The present study was conducted to determine the prevalence of PPE in HIV-infected patients and to correlate between the severity of PPE and individual CD4 count. MATERIALS AND METHODS: This was a cross-sectional study, conducted in Palakkad Antiretroviral Therapy Centre, Kerala, between March 2017 and April 2017. A total of 100 HIV patients with evidence of multiple itchy skin lesions of 1-month duration were included in the study. Severity of lesion was evaluated using an objective “rash severity scale” for PPE. Data were coded and analyzed. RESULTS: Prevalence of PPE was 11.35% in our study. The mean age of the study population was 41.17 ± 12. Male-to-female ratio was 1:2. In our study, 97% of the patients were giving history of mosquito bite. Most of the patients (40%) had moderate type of PPE. In our study, majority (86%) had a CD4 count of more than 200, and the incidence of PPE was more frequently seen in patients with CD4 count more than 200 cells which was statistically significant. CONCLUSION: PPEs are unique dermatosis, which is having a devastating impact on the quality of life, stigmatizing them in their communities. Thus, recognizing those lesions helps in allowing better treatment of this distressing condition.
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spelling pubmed-68963922020-01-09 Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study Mohammed, Shoubin Vellaisamy, Seethalakshmi Ganga Gopalan, Kannan Sukumaran, Lekha Valan, A. S. Indian J Sex Transm Dis AIDS Original Article INTRODUCTION: Pruritic papular eruption (PPE) remains as one of the most common cutaneous manifestations in HIV-infected patients. Proper knowledge about understanding the risk factors associated with this disease may help to decrease the prevalence of PPE. OBJECTIVE: The present study was conducted to determine the prevalence of PPE in HIV-infected patients and to correlate between the severity of PPE and individual CD4 count. MATERIALS AND METHODS: This was a cross-sectional study, conducted in Palakkad Antiretroviral Therapy Centre, Kerala, between March 2017 and April 2017. A total of 100 HIV patients with evidence of multiple itchy skin lesions of 1-month duration were included in the study. Severity of lesion was evaluated using an objective “rash severity scale” for PPE. Data were coded and analyzed. RESULTS: Prevalence of PPE was 11.35% in our study. The mean age of the study population was 41.17 ± 12. Male-to-female ratio was 1:2. In our study, 97% of the patients were giving history of mosquito bite. Most of the patients (40%) had moderate type of PPE. In our study, majority (86%) had a CD4 count of more than 200, and the incidence of PPE was more frequently seen in patients with CD4 count more than 200 cells which was statistically significant. CONCLUSION: PPEs are unique dermatosis, which is having a devastating impact on the quality of life, stigmatizing them in their communities. Thus, recognizing those lesions helps in allowing better treatment of this distressing condition. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6896392/ /pubmed/31922105 http://dx.doi.org/10.4103/ijstd.IJSTD_69_18 Text en Copyright: © 2019 Indian Journal of Sexually Transmitted Diseases and AIDS http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mohammed, Shoubin
Vellaisamy, Seethalakshmi Ganga
Gopalan, Kannan
Sukumaran, Lekha
Valan, A. S.
Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title_full Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title_fullStr Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title_full_unstemmed Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title_short Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study
title_sort prevalence of pruritic papular eruption among hiv patients: a cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896392/
https://www.ncbi.nlm.nih.gov/pubmed/31922105
http://dx.doi.org/10.4103/ijstd.IJSTD_69_18
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