PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin

BACKGROUND: Protein tyrosine phosphatase receptor delta (PTPRD) is frequently inactivated in various types of cancers. Here, we explored the underlying mechanism of PTPRD-loss-induced cancer metastasis and investigated an efficient treatment option for PTPRD-inactivated gastric cancers (GCs). METHOD...

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Detalles Bibliográficos
Autores principales: Bae, Won Jung, Ahn, Ji Mi, Byeon, Hye Eun, Kim, Seokwhi, Lee, Dakeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896474/
https://www.ncbi.nlm.nih.gov/pubmed/31805999
http://dx.doi.org/10.1186/s13046-019-1469-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896474/
https://www.ncbi.nlm.nih.gov/pubmed/31805999
http://dx.doi.org/10.1186/s13046-019-1469-4

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