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The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration

BACKGROUND: Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and generates ribose-5-phosphate and NADPH thereby governing ana...

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Detalles Bibliográficos
Autores principales:	Tu, Dezhen, Gao, Yun, Yang, Ru, Guan, Tian, Hong, Jau-Shyong, Gao, Hui-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896486/ https://www.ncbi.nlm.nih.gov/pubmed/31805953 http://dx.doi.org/10.1186/s12974-019-1659-1

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