Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!

The loss of dopaminergic neurons from the substantia nigra pars compacta characterizes the classical pathology of Parkinson's disease (PD). Deep brain stimulation (DBS) has become an increasingly common treatment for PD. Sometimes excessive tremors due to exacerbated PD hinder the surgery and m...

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Autores principales: Sokhal, Suman, Goyal, Keshav, Sokhal, Navdeep, Kumar, Niraj, Kedia, Shweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896633/
https://www.ncbi.nlm.nih.gov/pubmed/31903377
http://dx.doi.org/10.4103/ajns.AJNS_47_18
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author Sokhal, Suman
Goyal, Keshav
Sokhal, Navdeep
Kumar, Niraj
Kedia, Shweta
author_facet Sokhal, Suman
Goyal, Keshav
Sokhal, Navdeep
Kumar, Niraj
Kedia, Shweta
author_sort Sokhal, Suman
collection PubMed
description The loss of dopaminergic neurons from the substantia nigra pars compacta characterizes the classical pathology of Parkinson's disease (PD). Deep brain stimulation (DBS) has become an increasingly common treatment for PD. Sometimes excessive tremors due to exacerbated PD hinder the surgery and may almost make it impossible. This is a case report highlights use of IV ketamine for intraoperative sedation of a patient with PD, with severe dyskinesia & tremors, posted for DBS. IV ketamine resulted in prompt abolition of tremors and dyskinesia, which were unresponsive to previous traditional sedative drugs.
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spelling pubmed-68966332020-01-03 Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue! Sokhal, Suman Goyal, Keshav Sokhal, Navdeep Kumar, Niraj Kedia, Shweta Asian J Neurosurg Case Report The loss of dopaminergic neurons from the substantia nigra pars compacta characterizes the classical pathology of Parkinson's disease (PD). Deep brain stimulation (DBS) has become an increasingly common treatment for PD. Sometimes excessive tremors due to exacerbated PD hinder the surgery and may almost make it impossible. This is a case report highlights use of IV ketamine for intraoperative sedation of a patient with PD, with severe dyskinesia & tremors, posted for DBS. IV ketamine resulted in prompt abolition of tremors and dyskinesia, which were unresponsive to previous traditional sedative drugs. Wolters Kluwer - Medknow 2019-11-25 /pmc/articles/PMC6896633/ /pubmed/31903377 http://dx.doi.org/10.4103/ajns.AJNS_47_18 Text en Copyright: © 2019 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sokhal, Suman
Goyal, Keshav
Sokhal, Navdeep
Kumar, Niraj
Kedia, Shweta
Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title_full Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title_fullStr Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title_full_unstemmed Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title_short Intraoperative Management of a Patient for Deep Brain Stimulation with Severe Dyskinesia and Tremors: Ketamine to the Rescue!
title_sort intraoperative management of a patient for deep brain stimulation with severe dyskinesia and tremors: ketamine to the rescue!
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896633/
https://www.ncbi.nlm.nih.gov/pubmed/31903377
http://dx.doi.org/10.4103/ajns.AJNS_47_18
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