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Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital
OBJECTIVE: To determine the occurrence of anti-tuberculosis drug resistance and its association with sociodemographic and clinical characteristics of patients in a referral hospital. METHODS: This was a cross-sectional study based on data from patients who had mycobacterial culture identified and de...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Israelita de Ensino e Pesquisa Albert Einstein
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896654/ https://www.ncbi.nlm.nih.gov/pubmed/31664329 http://dx.doi.org/10.31744/einstein_journal/2020AO4620 |
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author | Bonin, Camilla Resende Fochat, Romário Costa Leite, Isabel Cristina Gonçalves Pereira, Thamiris Vilela Fajardo, Marina de Oliveira Pinto, Carmen Perches Gomide Macedo, Raquel Leite Silva, Marcio Roberto Menezes, Pillar Pace Lacerda de Araújo, Nilma Maria José Mendes da Costa, Ronaldo Rodrigues |
author_facet | Bonin, Camilla Resende Fochat, Romário Costa Leite, Isabel Cristina Gonçalves Pereira, Thamiris Vilela Fajardo, Marina de Oliveira Pinto, Carmen Perches Gomide Macedo, Raquel Leite Silva, Marcio Roberto Menezes, Pillar Pace Lacerda de Araújo, Nilma Maria José Mendes da Costa, Ronaldo Rodrigues |
author_sort | Bonin, Camilla Resende |
collection | PubMed |
description | OBJECTIVE: To determine the occurrence of anti-tuberculosis drug resistance and its association with sociodemographic and clinical characteristics of patients in a referral hospital. METHODS: This was a cross-sectional study based on data from patients who had mycobacterial culture identified and defined antimicrobials sensitivity profile (June 2014 to February 2016). The descriptive statistical analysis and Fisher’s exact test were used to compare proportions. RESULTS: The study included 104 patients who had positive results for Mycobacterium tuberculosis . Bacilloscopy had high positivity (93.3%). A total of 15 patients (14.4%) had resistant strains and six (5.6%) multidrug-resistant. The sociodemographic and clinical characteristics were not related with resistance. CONCLUSION: This study contributed to further the understandings about the tuberculosis patients’ profile, the study also served as a tool for development of specific public policies. Patients diagnosed with resistant tuberculosis must be under greater supervision. |
format | Online Article Text |
id | pubmed-6896654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
record_format | MEDLINE/PubMed |
spelling | pubmed-68966542019-12-24 Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital Bonin, Camilla Resende Fochat, Romário Costa Leite, Isabel Cristina Gonçalves Pereira, Thamiris Vilela Fajardo, Marina de Oliveira Pinto, Carmen Perches Gomide Macedo, Raquel Leite Silva, Marcio Roberto Menezes, Pillar Pace Lacerda de Araújo, Nilma Maria José Mendes da Costa, Ronaldo Rodrigues Einstein (Sao Paulo) Original Article OBJECTIVE: To determine the occurrence of anti-tuberculosis drug resistance and its association with sociodemographic and clinical characteristics of patients in a referral hospital. METHODS: This was a cross-sectional study based on data from patients who had mycobacterial culture identified and defined antimicrobials sensitivity profile (June 2014 to February 2016). The descriptive statistical analysis and Fisher’s exact test were used to compare proportions. RESULTS: The study included 104 patients who had positive results for Mycobacterium tuberculosis . Bacilloscopy had high positivity (93.3%). A total of 15 patients (14.4%) had resistant strains and six (5.6%) multidrug-resistant. The sociodemographic and clinical characteristics were not related with resistance. CONCLUSION: This study contributed to further the understandings about the tuberculosis patients’ profile, the study also served as a tool for development of specific public policies. Patients diagnosed with resistant tuberculosis must be under greater supervision. Instituto Israelita de Ensino e Pesquisa Albert Einstein 2019-10-22 /pmc/articles/PMC6896654/ /pubmed/31664329 http://dx.doi.org/10.31744/einstein_journal/2020AO4620 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Bonin, Camilla Resende Fochat, Romário Costa Leite, Isabel Cristina Gonçalves Pereira, Thamiris Vilela Fajardo, Marina de Oliveira Pinto, Carmen Perches Gomide Macedo, Raquel Leite Silva, Marcio Roberto Menezes, Pillar Pace Lacerda de Araújo, Nilma Maria José Mendes da Costa, Ronaldo Rodrigues Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title | Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title_full | Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title_fullStr | Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title_full_unstemmed | Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title_short | Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
title_sort | analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896654/ https://www.ncbi.nlm.nih.gov/pubmed/31664329 http://dx.doi.org/10.31744/einstein_journal/2020AO4620 |
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