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Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort

BACKGROUND: To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS: We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Ad...

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Autores principales: Hassiotis, Angela, Brown, Emma, Harris, James, Helm, David, Munir, Kerim, Salvador-Carulla, Luis, Bertelli, Marco, Baghdadli, Amaria, Wieland, Jannelien, Novell-Alsina, Ramon, Cid, Jordi, Vergés, Laura, Martínez-Leal, Rafael, Mutluer, Tuba, Ismayilov, Fuad, Emerson, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896708/
https://www.ncbi.nlm.nih.gov/pubmed/31805899
http://dx.doi.org/10.1186/s12888-019-2376-0
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author Hassiotis, Angela
Brown, Emma
Harris, James
Helm, David
Munir, Kerim
Salvador-Carulla, Luis
Bertelli, Marco
Baghdadli, Amaria
Wieland, Jannelien
Novell-Alsina, Ramon
Cid, Jordi
Vergés, Laura
Martínez-Leal, Rafael
Mutluer, Tuba
Ismayilov, Fuad
Emerson, Eric
author_facet Hassiotis, Angela
Brown, Emma
Harris, James
Helm, David
Munir, Kerim
Salvador-Carulla, Luis
Bertelli, Marco
Baghdadli, Amaria
Wieland, Jannelien
Novell-Alsina, Ramon
Cid, Jordi
Vergés, Laura
Martínez-Leal, Rafael
Mutluer, Tuba
Ismayilov, Fuad
Emerson, Eric
author_sort Hassiotis, Angela
collection PubMed
description BACKGROUND: To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS: We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. RESULTS: Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104–0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. CONCLUSIONS: The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group.
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spelling pubmed-68967082019-12-11 Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort Hassiotis, Angela Brown, Emma Harris, James Helm, David Munir, Kerim Salvador-Carulla, Luis Bertelli, Marco Baghdadli, Amaria Wieland, Jannelien Novell-Alsina, Ramon Cid, Jordi Vergés, Laura Martínez-Leal, Rafael Mutluer, Tuba Ismayilov, Fuad Emerson, Eric BMC Psychiatry Research Article BACKGROUND: To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS: We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. RESULTS: Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104–0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. CONCLUSIONS: The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group. BioMed Central 2019-12-05 /pmc/articles/PMC6896708/ /pubmed/31805899 http://dx.doi.org/10.1186/s12888-019-2376-0 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hassiotis, Angela
Brown, Emma
Harris, James
Helm, David
Munir, Kerim
Salvador-Carulla, Luis
Bertelli, Marco
Baghdadli, Amaria
Wieland, Jannelien
Novell-Alsina, Ramon
Cid, Jordi
Vergés, Laura
Martínez-Leal, Rafael
Mutluer, Tuba
Ismayilov, Fuad
Emerson, Eric
Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title_full Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title_fullStr Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title_full_unstemmed Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title_short Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
title_sort association of borderline intellectual functioning and adverse childhood experience with adult psychiatric morbidity. findings from a british birth cohort
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896708/
https://www.ncbi.nlm.nih.gov/pubmed/31805899
http://dx.doi.org/10.1186/s12888-019-2376-0
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