Expression of a recombinant bacterial l-asparaginase in human cells

OBJECTIVE: l-Asparaginase (ASNase) is an enzyme used in the treatment of acute lymphoblastic leukemia (ALL). As the therapeutic ASNases has bacterial origin, severe side effects are associated with its use, among them hypersensitivity and inactivation of the enzyme. In this context, the objective of...

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Detalles Bibliográficos
Autores principales: Dantas, Raquel Caminha, Caetano, Ludmilla Freire, Torres, Ariany Lima Sousa, Alves, Matheus Soares, Silva, Emanuelly Thays Muniz Figueiredo, Teixeira, Louhanna Pinheiro Rodrigues, Teixeira, Daniel Câmara, de Azevedo Moreira, Renato, Fonseca, Marcela Helena Gambim, Gaudêncio Neto, Saul, Martins, Leonardo Tondello, Furtado, Gilvan Pessoa, Tavares, Kaio Cesar Simiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896745/
https://www.ncbi.nlm.nih.gov/pubmed/31806048
http://dx.doi.org/10.1186/s13104-019-4836-5

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