Cargando…
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration
CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutations within the CBP gene are known to cause Rubinstein-Taybi syndrome (RSTS), a developmental...
Autores principales: | Schoof, Melanie, Launspach, Michael, Holdhof, Dörthe, Nguyen, Lynhda, Engel, Verena, Filser, Severin, Peters, Finn, Immenschuh, Jana, Hellwig, Malte, Niesen, Judith, Mall, Volker, Ertl-Wagner, Birgit, Hagel, Christian, Spohn, Michael, Lutz, Beat, Sedlacik, Jan, Indenbirken, Daniela, Merk, Daniel J., Schüller, Ulrich |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896766/ https://www.ncbi.nlm.nih.gov/pubmed/31806049 http://dx.doi.org/10.1186/s40478-019-0849-5 |
Ejemplares similares
-
MEDB-12. Severe developmental abnormalities and proliferative cerebellar lesions induced by combined activity of Wnt signalling and loss of SMARCA4
por: Göbel, Carolin, et al.
Publicado: (2022) -
Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration
por: Holdhof, Dörthe, et al.
Publicado: (2021) -
MEDB-11. MYC overexpression and SMARCA4 loss in cerebellar granule cell precursors cooperate to drive medulloblastoma formation in mice
por: Göbel, Carolin, et al.
Publicado: (2022) -
Alcohol-Induced Neuroadaptation Is Orchestrated by the Histone Acetyltransferase CBP
por: Ghezzi, Alfredo, et al.
Publicado: (2017) -
The Transcriptional Coactivator Cbp Interacts with β-Catenin to Activate Gene Expression
por: Takemaru, Ken-Ichi, et al.
Publicado: (2000)