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Inhibition of KPNB1 Inhibits Proliferation and Promotes Apoptosis of Chronic Myeloid Leukemia Cells Through Regulation of E2F1

BACKGROUND: Karyopherin-β1 (KPNB1) belongs to the karyopherin superfamily, which functions as shuttling proteins from the cytoplasm to nuclear. A high level of KPNB1 has been reported in various cancers which promotes cell proliferation and inhibits apoptosis. However, the role of KPNB1 in chronic m...

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Detalles Bibliográficos
Autores principales:	Wang, Teng, Huang, Zhenglan, Huang, Ningshu, Peng, Yuhang, Gao, Miao, Wang, Xin, Feng, Wenli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896920/ https://www.ncbi.nlm.nih.gov/pubmed/31819526 http://dx.doi.org/10.2147/OTT.S210048

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