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Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis()

BACKGROUND AND AIM: Pyruvate dehydrogenase kinase 4 (PDK4) is a metabolism switch that regulates glucose oxidation and the tricarboxylic acid cycle (TCA cycle) in the mitochondria. Liver detoxifies xenobiotics and is constantly challenged by various injuries. This study aims at understanding how the...

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Detalles Bibliográficos
Autores principales:	Choiniere, Jonathan, Lin, Matthew Junda, Wang, Li, Wu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896988/ https://www.ncbi.nlm.nih.gov/pubmed/31815032 http://dx.doi.org/10.1016/j.livres.2018.05.001

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