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Inhibition of Colorectal Cancer Cell Proliferation by Regulating Platelet-Derived Growth Factor B Signaling with a DNA Aptamer

BACKGROUND: Overexpression of platelet-derived growth factor-BB (PDGF-BB) is associated with colorectal carcinogenesis. PDGF-BB plays a role in the autocrine growth stimulation of cancer cells. Aptamers are short single-stranded oligonucleotides that can bind to cellular targets with high affinity a...

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Detalles Bibliográficos
Autores principales:	Sae-Lim, Suvaraporn, Soontornworajit, Boonchoy, Pichayanoot, Pichayanoot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897029/ https://www.ncbi.nlm.nih.gov/pubmed/30803211 http://dx.doi.org/10.31557/APJCP.2019.20.2.487

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